Myelostat® Capsules contain Hydroxyurea, an antimetabolite anticancer agent used in the treatment of various hematological disorders and certain malignancies. It works by inhibiting DNA synthesis, thereby reducing the proliferation of rapidly dividing abnormal cells.
Hydroxyurea is also widely used in selected non-malignant hematological conditions under strict medical supervision.
💊 Uses / Indications
Chronic Myeloid Leukemia (CML)
Polycythemia Vera
Essential Thrombocythemia
Sickle Cell Anemia (to reduce frequency of painful crises)
Other hematological disorders as prescribed
⚙️ Mechanism of Action
Hydroxyurea inhibits ribonucleotide reductase, an enzyme essential for DNA synthesis. This results in decreased DNA replication in rapidly dividing cells, leading to reduced abnormal cell growth.
🧪 Dosage & Administration
Take as directed by the physician
Dosage is individualized based on condition and blood counts
Capsule should be swallowed whole
Do not open, crush, or chew the capsule
⚠️ Possible Side Effects
Bone marrow suppression
Nausea or vomiting
Diarrhea or constipation
Skin rash or pigmentation changes
Fatigue
Increased risk of infection
🚫 Precautions & Warnings
Prescription-only medicine
Regular blood count monitoring required
Use with caution in patients with renal or hepatic impairment
Not recommended during pregnancy or breastfeeding
Avoid handling broken capsules
❄️ Storage Instructions
Store below 25°C
Protect from heat, light, and moisture
Keep out of reach of children
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