Janumet Tablets contain a combination of Metformin and Sitagliptin, used for the management of type 2 diabetes mellitus. This dual-action therapy helps improve blood glucose control by reducing glucose production in the liver and enhancing insulin release after meals, making it effective when diet and exercise alone are not sufficient.

Uses / Indications

• Type 2 diabetes mellitus

• Improves glycemic control along with diet and exercise

Mechanism of Action

• Metformin reduces hepatic glucose production and improves insulin sensitivity

• Sitagliptin (DPP-4 inhibitor) increases incretin levels, enhancing insulin secretion and reducing glucagon release
  Together, they help maintain stable blood sugar levels.

Dosage & Administration

• To be taken as prescribed by a physician

• Usually taken with meals to reduce gastric discomfort

Possible Side Effects

• Nausea

• Diarrhea

• Abdominal discomfort

• Headache

• Low blood sugar (when combined with other antidiabetics)

Precautions & Warnings

• Not recommended in severe kidney impairment

• Use with caution in elderly patients

• Avoid excessive alcohol consumption

• Regular monitoring of blood glucose and kidney function advised

Storage Instructions

• Store below 30°C

• Protect from moisture and light

• Keep out of reach of children

Regulatory Information

• Rx only (Prescription medicine)

• For oral use only