Vymada 50 mg Tablets contain a fixed-dose combination of Sacubitril and Valsartan, used primarily in the management of chronic heart failure. This medicine works by enhancing protective neurohormonal systems while simultaneously blocking harmful effects of the renin-angiotensin system, helping improve heart function and reduce hospitalization risk in heart failure patients.
Uses / Indications
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Chronic heart failure (reduced ejection fraction)
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To lower the risk of cardiovascular death and hospitalization due to heart failure
Mechanism of Action
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Sacubitril inhibits neprilysin, increasing levels of beneficial peptides that cause vasodilation and sodium excretion
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Valsartan blocks angiotensin II receptors, reducing blood pressure and strain on the heart
Together, they improve cardiac efficiency and reduce disease progression.
Dosage & Administration
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Dosage as prescribed by a physician
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Usually taken once or twice daily
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Can be taken with or without food
Possible Side Effects
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Low blood pressure (hypotension)
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Dizziness
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Increased potassium levels
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Kidney function changes
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Cough
(Not everyone experiences side effects)
Precautions & Warnings
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Not recommended during pregnancy
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Use with caution in kidney or liver impairment
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Avoid combining with ACE inhibitors without proper washout period
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Regular monitoring of blood pressure and kidney function advised
Storage Instructions
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Store below 30°C
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Protect from moisture and light
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Keep out of reach of children
Regulatory Information
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Rx only (Prescription medicine)
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For sale in India only
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