Leucovorin Calcium 15 mg Tablet (Calcium Folinate / Leucovorin USP 15 mg)

Leucovorin Calcium 15 mg Tablet contains Calcium Folinate (Leucovorin USP 15 mg), a folate analog used as a rescue and supportive therapy in oncology and hematology. It helps protect healthy cells from the toxic effects of certain chemotherapy drugs, especially methotrexate, and supports folate metabolism in patients with deficiency.

This medicine is widely prescribed in the management of methotrexate toxicity, folate-deficiency anemia, and cancer supportive care. Leucovorin Calcium 15 mg enhances chemotherapy effectiveness in combination treatments, such as with 5-fluorouracil, while minimizing adverse effects on normal cells.

⚠️ Prescription-only medicine. To be used strictly under medical supervision.

💊 Composition

Each tablet contains:

• Leucovorin Calcium (Calcium Folinate) USP – 15 mg

• Excipients: q.s.

🩺 Uses of Leucovorin Calcium 15 mg Tablet

• Rescue therapy after high-dose methotrexate administration

• Treatment of folate-deficiency anemia and megaloblastic anemia

• Supportive care in cancer chemotherapy (enhances 5-FU effects)

• Protection of normal cells during chemotherapy regimens

⚙️ Mechanism of Action

Leucovorin bypasses the metabolic blockade caused by methotrexate, restoring folate-dependent enzymatic reactions necessary for DNA and RNA synthesis. It selectively protects normal cells without reducing the effectiveness of anticancer drugs.

📦 Dosage & Administration

• Dosage is individualized according to medical condition and physician instructions

• Take exactly as prescribed

• Swallow tablet whole with water

• Do not crush, chew, or alter the tablet

⚠️ Precautions & Warnings

• Not recommended during pregnancy or breastfeeding unless prescribed

• Regular blood monitoring is required during treatment

• Use with caution in patients with vitamin B12 deficiency or other metabolic disorders

• Avoid self-medication; follow physician guidance strictly

❌ Possible Side Effects

• Mild nausea or vomiting

• Diarrhea

• Allergic reactions such as rash or itching

• Rare headache or fatigue

(Consult a doctor if side effects persist or worsen.)

🏭 Storage Instructions

• Store below 25°C

• Protect from light and moisture

• Keep out of reach of children

📌 Disclaimer

This information is for educational purposes only and does not replace medical advice. Always consult a qualified healthcare professional before using this medicine.