Enzamide-40 Capsules contain Enzalutamide, a potent androgen receptor inhibitor used in the treatment of advanced prostate cancer. It works by blocking the effect of male hormones (androgens) that stimulate the growth of prostate cancer cells. This medication is commonly prescribed in metastatic and castration-resistant prostate cancer cases.
Uses / Indications
Enzamide-40 is indicated for the treatment of:
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Metastatic castration-resistant prostate cancer (mCRPC)
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Metastatic hormone-sensitive prostate cancer (mHSPC)
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Advanced prostate cancer in patients progressing despite androgen deprivation therapy
Mechanism of Action
Enzalutamide inhibits androgen receptor signaling by:
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Preventing androgen binding to androgen receptors
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Inhibiting nuclear translocation of activated receptors
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Blocking androgen receptor interaction with DNA
This results in suppression of prostate cancer cell growth and proliferation.
Dosage & Administration
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Recommended Dose: As prescribed by the oncologist
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Capsules should be swallowed whole with water
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Do not open, chew, or crush the capsules
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Can be taken with or without food
⚠️ Dose adjustment is strictly based on medical supervision
Side Effects
Common side effects may include:
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Fatigue
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Hot flashes
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Weakness
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Dizziness
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High blood pressure
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Headache
Less common but serious effects:
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Seizures
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Falls and fractures
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Cardiovascular events
Precautions & Warnings
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For use only under specialist supervision
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Not recommended in patients with seizure disorders
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Use caution in patients with cardiovascular disease
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Women who are pregnant or may become pregnant should not handle capsules
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Avoid driving or operating machinery if dizziness occurs
Drug Interactions
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May interact with anticonvulsants
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Caution with drugs affecting CYP enzymes
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Inform your doctor about all ongoing medications
Storage Instructions
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Store below 25°C
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Keep away from moisture and direct sunlight
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Keep out of reach of children
Key Highlights
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Advanced therapy for prostate cancer
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Strong androgen receptor inhibitor
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Oral administration for patient convenience
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Clinically proven efficacy
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Prescription-only oncology medicine

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