Enbendazole 1000 mg – Anthelmintic Oral Tablet

Enbendazole 1000 mg is a potent anthelmintic oral tablet used to treat a wide range of parasitic worm infections. This medication works by disrupting the energy metabolism of worms, leading to their elimination from the body.

It is suitable for treating intestinal worms, tapeworms, and other parasitic infections, providing a safe and effective solution for both adults and children (age and dosage permitting).

Uses of Enbendazole 1000 mg

Approved Uses

• Treatment of roundworm (Ascaris lumbricoides) infections

• Treatment of hookworm (Ancylostoma, Necator) infections

• Tapeworm (Taenia) infections

• Whipworm (Trichuris trichiura) infections

Supportive / Off-Label Uses

• Prevention of parasitic reinfection in endemic areas

• Treatment of certain liver fluke infections (under medical supervision)

Mechanism of Action

Enbendazole 1000 mg works by inhibiting microtubule formation in parasitic worms, preventing their ability to absorb glucose. This disruption depletes the parasite’s energy supply, causing immobilization and eventual death.

Dosage & Administration

• Typical adult dose: 1000 mg orally as a single dose or as prescribed by a physician

• For children: dose varies depending on weight and age

• Tablets can be taken with water, with or after meals to reduce stomach upset

• Repeat doses may be recommended for certain infections as per doctor’s instructions

Common Side Effects

• Nausea or mild stomach upset

• Diarrhea

• Mild headache

• Rare dizziness or fatigue

Serious Side Effects

• Allergic reactions including rash, itching, or swelling

• Severe abdominal pain or persistent vomiting

• Liver enzyme abnormalities in prolonged use

Drug Interactions

• Cimetidine: May increase drug levels in the blood

• Anticonvulsants (Phenytoin, Carbamazepine): Can reduce Albendazole effectiveness

• Other anti-parasitic drugs: Use as advised by a physician

Food & Lifestyle Interactions

• Can be taken with meals to reduce stomach upset

• Maintain adequate hydration

• Follow hygienic practices to prevent reinfection

Monitoring & Tests

• Liver function tests if used for prolonged therapy

• Regular stool tests to confirm parasite clearance

Precautions & Warnings

• Not recommended for use during pregnancy, especially in the first trimester

• Use with caution in individuals with liver disease

• Consult a doctor before use in children under recommended age