Tamlong-20 Tablets contain Tamoxifen Citrate, a selective estrogen receptor modulator (SERM) widely used in the treatment and prevention of estrogen receptor-positive breast cancer. It works by blocking the effects of estrogen on breast tissue, thereby slowing or stopping the growth of hormone-dependent cancer cells.

Uses / Indications

Tamlong-20 is indicated for:

• Estrogen receptor-positive breast cancer (early & advanced stages)

• Adjuvant therapy after breast cancer surgery

• Prevention of breast cancer in high-risk women

• Treatment of metastatic breast cancer

• Infertility related to ovulation disorders (off-label, as prescribed)

Mechanism of Action

Tamoxifen acts by competitively binding to estrogen receptors in breast tissue.
This results in:

• Blocking estrogen-stimulated cancer cell growth

• Reduction in tumor progression

• Anti-estrogenic effect on breast tissue

• Partial estrogen-like effects on bone and lipid metabolism

Dosage & Administration

• Typical dose: 20 mg once daily or as prescribed

• Can be taken with or without food

• Duration depends on condition and clinical response

⚠️ Always follow the dosage prescribed by the oncologist or physician.

Side Effects

Common side effects:

• Hot flashes

• Nausea

• Fatigue

• Menstrual irregularities

Less common:

• Leg cramps

• Headache

• Vaginal discharge or dryness

Serious but rare:

• Blood clots (DVT, pulmonary embolism)

• Endometrial changes

• Visual disturbances

Precautions & Warnings

• Increased risk of thromboembolic events

• Use with caution in patients with history of blood clots

• Regular gynecological and ophthalmic checkups advised

• Not recommended during pregnancy

• Prescription-only medicine

Drug Interactions

• Anticoagulants (e.g., warfarin)

• Certain antidepressants (CYP2D6 inhibitors)

• Hormonal therapies

Inform your doctor about all medicines being taken.

Storage Instructions

• Store below 25°C

• Protect from moisture and light

• Keep out of reach of children

Key Highlights

• Gold-standard therapy for hormone-positive breast cancer

• Proven long-term survival benefit

• Also helps reduce breast cancer recurrence

• Trusted formulation by IPCA

• Oral, convenient dosing